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1.
COVID-19 in Alzheimer's Disease and Dementia ; : 159-167, 2023.
Article in English | Scopus | ID: covidwho-20242441

ABSTRACT

The coronavirus (COVID-19) pandemic has exposed and highlighted pre-existing psychiatric illness in the elderly as well as predisposed them to new and emerging psychiatric pathology. The impact of this devastating illness has been felt in each setting including nursing homes and prisons and has been a barrier toward healthy aging. Despite the many challenges faced by our elderly, resilience and wisdom have served as protective factors in our fight against the pandemic. This chapter highlights the psychiatric effects of the illness and ways to manage the burden associated with psychopathology. © 2023 Elsevier Inc. All rights reserved.

2.
Cancer Research, Statistics, and Treatment ; 6(1):52-61, 2023.
Article in English | EMBASE | ID: covidwho-20242251

ABSTRACT

Background: Older patients with cancer are at a higher risk of invasive infections. Vaccination is an effective approach to decrease the mortality and morbidity associated with infections. Objective(s): Our primary objective was to evaluate the proportion of older patients with cancer who had received routine vaccinations against pneumococcal, influenza, and coronavirus disease 2019 (COVID-19). Our secondary objective was to identify the factors associated with vaccine uptake such as age, sex, education, marital status, comorbidities, and place of residence. Material(s) and Method(s): This cross-sectional observational study was conducted in the geriatric oncology outpatient clinic of the Department of Medical Oncology at the Tata Memorial Hospital, a tertiary care cancer hospital in Mumbai, India, from February 2020 to January 2023. We included all patients aged >=60 years who were evaluated in the geriatric oncology clinic during the study period and for whom the immunization details were available. The uptake of COVID-19 vaccine was calculated from March 2021 onwards, which was when the COVID-19 vaccine became available to patients aged >=60 years in India. Result(s): We enrolled 1762 patients;1342 (76.2%) were male. The mean age was 68.4 (SD, 5.8) years;795 (45%) patients were from the west zone of India. Only 12 (0.68%) patients had received the pneumococcal vaccine, and 13 (0.7%) had received the influenza vaccine. At least one dose of the COVID-19 vaccine had been taken by 1302 of 1562 patients (83.3%). On univariate logistic regression, education, marital status, geographic zone of residence, and primary tumor site were correlated with the uptake of COVID-19 vaccine. Factors associated with a greater COVID-19 vaccine uptake included education (up to Std 10 and higher vs. less than Std 10: Odds Ratio [OR], 1.46;95% confidence interval [CI], 1.07-1.99;P = 0.018, and illiterate vs. less than Std 10: OR, 0.70;95% CI, 0.50-0.99;P = 0.041), marital status (unmarried vs. married: OR, 0.27;95% CI, 0.08-1.08;P = 0.046, and widow/widower vs. married: OR, 0.67;95% CI, 0.48-0.94;P = 0.017), lung and gastrointestinal vs. head-and-neck primary tumors (lung cancer vs. head-and-neck cancer: OR, 1.60;95% CI, 1.02-2.47;P = 0.038, and gastrointestinal vs.head-and-neck cancer: OR, 2.18;95% CI, 1.37-3.42;P < 0.001), and place of residence (west zone vs. central India: OR, 0.34;95% CI, 0.13-0.75;P = 0.015). Conclusion(s): Fewer than 1 in 100 older Indian patients with cancer receive routine immunization with influenza and pneumococcal vaccines. Hearteningly, the uptake of COVID-19 vaccination in older Indian patients with cancer is over 80%, possibly due to the global recognition of its importance during the pandemic. Similar measures as those used to increase the uptake of COVID-19 vaccines during the pandemic may be beneficial to increase the uptake of routine vaccinations.Copyright © 2023 Cancer Research, Statistics, and Treatment.

3.
Cancer Research, Statistics, and Treatment ; 5(1):163-164, 2022.
Article in English | EMBASE | ID: covidwho-20241500
4.
Universa Medicina ; 42(1):101-107, 2023.
Article in English | Web of Science | ID: covidwho-20241043

ABSTRACT

BACKGROUND The severity of COVID-19 infection has an increasing trend in the elderly, which contributes to the high morbidity and mortality rates in this population. Aging itself is a prominent risk factor for severe disease and death from COVID-19. CASEDESCRIPTION This case report a 71-year-old woman who complained of shortness of breath for 3 days before being admitted to the hospital. Bilateral consolidation and increased bronchovascular pattern were found on chest radiograph, and a positive SARS-COV2 nasopharyngeal swab PCR test result was noted. This patient was diagnosed with confirmed severe manifestation of COVID-19, community-acquired pneumonia and type 1 respiratory failure, as well as type II diabetes mellitus and suspicion of acute gastritis. The results of the geriatric status assessment were moderate functional status, risk of malnutrition, and moderate risk of deep vein thrombosis (DVT). This patient underwent treatment in accordance with the COVID-19 protocol along with management for geriatric status improvement. The patient was given permission to return home after 14 days of treatment, during which time her health had improved and her functional status had changed to moderate dependency. During follow-up, the patient continued to receive therapy. She is still being observed and future evaluations will be conducted. CONCLUSION The increased susceptibility of the elderly to COVID-19 infection is caused by various factors. A burden of death and long-term disability brought on by this pandemic may be lessened by new or modified therapies that target aging-associated mechanisms. Therefore, COVID-19 case management in this population should be done with a comprehensive approach.

5.
Cancer Research, Statistics, and Treatment ; 4(2):370-373, 2021.
Article in English | EMBASE | ID: covidwho-20239605
6.
Early Intervention in Psychiatry ; 17(Supplement 1):259, 2023.
Article in English | EMBASE | ID: covidwho-20237935

ABSTRACT

Aims: The impacts of the coronavirus disease of 2019 (COVID-19) pandemic on mental health have been relatively severe. This study examined the influence of the COVID-19 especially on depression and suicidal ideation in community-dwelling elderly in Korea. Method(s): Data were employed from a survey on elderly mental health in Jeollanam-do (southwest province in Korea). A total of 2423 elderlies were recruited from 22 counties in Jeollanam-do between April and October 2021. We used self-reported questionnaires, including sociodemographic factors, COVID-19 related stress, suicidal ideation, Geriatric Depression Scale-Short Form Korean Version (GDS-SF). Logistic regression was performed to examine the factors on depression and suicidal ideation. Result(s): Of the 2423 subjects, 622 (25.7%) reported depressive symptoms and 518 (21.4%) reported suicidal ideation. The multivariate logistic regression analysis revealed that living alone, poor perceived health status, the worry of COVID-19 infection and restriction of daily activity due to COVID-19 pandemic were significantly associated with depression. Male sex, poor perceived health status, disability in house chores and depressive symptom are risk factors for suicidal ideation. Conclusion(s): These findings showed that increased risk factor for depression and suicidal ideation in community dwelling elderly during COVID-19 pandemic. We confirmed that feelings of isolation and negative perception of health were risk factors on depression in community dwelling elderly in the context of the COVID -19 pandemic. Also male, poor self-perceived health status, difficulty of independent living and worry and depression are increased the risk of suicidal ideation among the elderly.

7.
Acta Clinica Croatica ; 61(4):655-660, 2022.
Article in English | EMBASE | ID: covidwho-20236092

ABSTRACT

In our study, we examined the effect of COVID-19 vaccination on the incidence of pneumothorax in intensive care patients over age 65. COVID-19 intensive care patients that presented to our department between April 2020 and May 2021 during the COVID-19 pandemic were evaluated retrospectively. Patients were divided into two main groups, i.e., before and after the vaccination period. Patients were evaluated retrospectively for the following parameters: Gender, age, side of pneumothorax, mortality, discharge, comorbidity, and additional pleural complications. The total number of patients was 87, i.e., 66 patients before vaccination and 21 patients after vaccination. When patients in the pre- and post-vaccination period were compared, there was a significant difference in the incidence of pneumothorax between the two groups (p<0.05). Pneumothorax was less common after vaccination. When patients with pneumothorax and tube thoracostomy were evaluated according to pre- and post-vaccination mortality, mortality was significantly higher (89%) in the pre-vaccination period (p<0.05). We consider that COVID-19 vaccines used in patients aged over 65 reduced the incidence of pleural complications, especially pneumothorax. We think that mortality due to pneumothorax in patients over 65 years of age was lower during the vaccination period. In addition, we think that bilateral pneumothorax was more common in the non-vaccinated period. As a result, we think that life-threatening pneumothorax and similar complications could be reduced by increasing the number of vaccines made in the COVID-19 pandemic and spreading it around the world.Copyright © 2022, Dr. Mladen Stojanovic University Hospital. All rights reserved.

8.
Aging Psychology ; 8(3):235-249, 2022.
Article in Persian | APA PsycInfo | ID: covidwho-20235314

ABSTRACT

The coronavirus disease, as an emerging disease with global spread and high mortality rates among vulnerable groups, in addition to physical symptoms, has led to the occurrence of many psychological disorders such as death anxiety and feeling of loneliness due to the fear of infection. Therefore, the purpose of this study was to compare the effectiveness of group logotherapy and solution-oriented therapy on anxiety and feeling of loneliness in the elderly with the fear of coronavirus. The research method was quasi-experimental with pretest-posttest and a control group design. The statistical population consisted of the elderly women who took part in the daily rehabilitation centers of the Welfare Institution (Sazman-e Behzisti), in Tabriz, among whom 36 eligible individuals were selected and randomly assigned into two experimental and one control groups. measuers applied in the current study incuded Templer's Death Anxiety Scale and Russell et al.'s UCLA Loneliness Scale. The experimental groups underwent ten 90-minute therapy sessions, separately and with two different approaches, while the control group did not receive any intervention at the same time. The data were analysed using analysis of covariance (ANCOVA) in SPSS-24 software. The results indicated that logotherapy and Solution-oriented therapy have a significant effect on reducing death anxiety and feeling of loneliness (P <= 0.05). Although, there was no significant difference between two experimental groups in reducing death anxiety (P >= 0.05), there was a significant difference between the two experimental groups in reducing loneliness, in a way that the effectiveness of logotherapy was greater (P <= 0.05). According to the results, logotherapy and solution-oriented therapy can be applied to improve the death anxiety and feeling of loneliness among elderly women with fear of coronavirus. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

9.
ACTA Paulista de Enfermagem ; 35, 2022.
Article in English | Scopus | ID: covidwho-20232735

ABSTRACT

Objective: To assess influenza vaccination coverage and reasons for vaccination or not in older adults, in the campaigns of 2019 and 2020. Methods: This is a quantitative and longitudinal study, carried out in Tres Lagoas (MS). Older adults registered in health care or social services participated. In the first quarter of 2020, 172 older adults were assessed in person, of whom 86 were re-interviewed between August and October 2020 through telephone contact. In the first interview, questions were asked about the flu vaccination in 2019 and the reasons for vaccination or not. In the second, the questions were about vaccination in 2020 and why. Vaccination coverage for 2019 and 2020 was compared using the McNemar test. Results: There was a predominance of women, with an average age of 69.1 years. Vaccination coverage in 2019 was 90.7%. Most of them took the vaccine because they believed it was important. As reasons for non-vaccination, the previous reactions and the fact that they did not have the flu were highlighted. In 2020, coverage was 86.0%. Most older adults were vaccinated because the vaccine was available in the Unified Health System (Sistema Único de Saúde). The reasons for non-vaccination were fear of leaving home due to the pandemic and lack of professional guidance. There was no significant difference in vaccination coverage in 2019 and 2020 (p=0.388). Conclusion: Vaccination coverage decreased in the year of the pandemic, with no significant difference. Reliable information from healthcare professionals and the media is essential for maintaining high vaccination coverage. © 2022 Departamento de Enfermagem/Universidade Federal de Sao Paulo. All rights reserved.

10.
BMJ Open ; 13(6): e072029, 2023 06 01.
Article in English | MEDLINE | ID: covidwho-20243589

ABSTRACT

INTRODUCTION: Falls are an important public health issue with consequences that include injuries, quality of life reduction and high healthcare costs. Studies show that falls prevention strategies are effective in reducing falls rate among community-dwelling older adults. However, the evaluation for effectiveness was usually done in a controlled setting with homogeneous population, and thus may not be generalisable to a wider population. This study aims to evaluate the impact of community falls prevention programmes with group-based strength and balance exercises, on falls risk and health outcomes for older adults with falls risk in Singapore. METHODS AND ANALYSIS: This is a pragmatic closed cohort stepped-wedge cluster randomised trial design study, which involves sequential crossover of clusters from the waitlist control condition to the intervention condition, with the sequence of crossover randomly determined. The intervention will be sequentially rolled out to 12 clusters (a minimum of 5 participants/cluster), over 6 time periods with 8-week intervals in Central and North regions of Singapore. The primary analysis will be conducted under the intention-to-treat principle. A general linear mixed model or generalised estimating equation analysis appropriate for a multilevel longitudinal study incorporating an appropriate error distribution and link function will be used. Markov model will be developed to estimate the incremental cost per quality-adjusted life years and incremental cost per fall prevented from the implementation of falls prevention strategies from a societal perspective. Conditional on there being clinically relevant differences in short-term outcomes, we will implement simulation modelling to project the long-term divergence in trajectories for outcomes and costs using the Markov model. ETHICS AND DISSEMINATION: Ethics approval has been obtained. Results will be disseminated in publications and other relevant platforms. TRIAL REGISTRATION NUMBER: NCT04788251.


Subject(s)
Exercise Therapy , Quality of Life , Humans , Aged , Longitudinal Studies , Singapore , Exercise Therapy/methods , Randomized Controlled Trials as Topic , Multicenter Studies as Topic
11.
J Frailty Sarcopenia Falls ; 8(2): 74-82, 2023 Jun.
Article in English | MEDLINE | ID: covidwho-20235305

ABSTRACT

Objectives: To identify which risk factors were associated with developing Coronavirus Disease-19 (COVID-19) infection, with symptoms, in institutionalized older people. Methods: A 1-year longitudinal multi-center study was conducted in 5 nursing homes (NHs) over the period December 2019 to March 2021. Inclusion criteria included being a permanent resident in the NH, aged 65 years or older, and a positive diagnosis of COVID-19 objectively confirmed by a diagnostic test. A descriptive and bivariate analysis was performed, calculating relative risk (RR) with 95% confidence intervals and statistical significance at p<0.05. Results: Of the total sample of 78 individuals who tested positive for COVID-19, the mean age was 84.6 years (SD=±7.8), 62 (79.5%) were female; 40 (51.3%) participants presented with COVID-19 symptoms. Living in a private NH (RR=3.6, 95% CI [1.2-11.0], p=0.023) and having suffered a stroke (RR=4.1, 95% CI [1.1-14.7], p=0.033) were positively associated with developing COVID-19 infection with symptoms. Conclusions: Having suffered a stroke and living permanently in a private NH were positively associated with symptomatic COVID-19 in this sample of institutionalized older people.Clinical Trials ID: NCT04297904.

12.
Curr Treat Options Psychiatry ; : 1-20, 2023 Jun 05.
Article in English | MEDLINE | ID: covidwho-20238728

ABSTRACT

Purpose of review: Substance use disorders are becoming increasingly prevalent in the geriatric population, necessitating an updated understanding of the existing literature. This review aims to describe the epidemiology, special considerations, and management of substance use disorders in older adults. Recent findings: PubMed, Ovid MEDLINE, and PsychINFO databases were searched from their inception through June 2022 using the following keywords: "substance use disorder," "substance abuse," "abuse," "illicit substances," "illicit drugs," "addiction," "geriatric," "elderly," "older adults," "alcohol," "marijuana," "cannabis," "cocaine," "heroin," "opioid," and "benzodiazepine." Our findings suggest an increasing trend in substance use in older adults despite medical and psychiatric consequences when using such substances. The majority of older patients admitted to substance abuse treatment programs were not referred by healthcare providers, suggesting room for improvement in the screening and discussion of substance use disorders. Our review also suggests that there should be careful consideration of COVID-19 and racial disparities when screening, diagnosing, and treating substance use disorders in the older population. Summary: This review provides updated information on epidemiology, special considerations, and management of substance use disorders in older adults. As substance use disorders become more prevalent in older adults, primary care physicians must be prepared to recognize and diagnose substance use disorders as well as collaborate with and refer patients to geriatric medicine, geriatric psychiatry, and addiction medicine.

13.
BMC Geriatr ; 23(1): 341, 2023 05 31.
Article in English | MEDLINE | ID: covidwho-20237140

ABSTRACT

BACKGROUND: Under the state of emergency, it has been reported that the amount of physical activity among community-dwelling older adults has decreased significantly due to refraining from going out, and there are strong concerns about the Geriatric Locomotive Function Scale and deterioration of mental health. Therefore, this study aimed to investigate whether the depressive state before the coronavirus disease 2019 (COVID-19) pandemic affected the 25-Geriatric Locomotive (GLFS) score during the COVID-19 pandemic among community-dwelling older adults. METHODS: The participants were 194 community-dwelling older adults (45 men, 149 women) with an average age of 75.5 ± 5.5 years who responded to a self-administered survey conducted three times (preliminary, second, and third) from before the 2018 COVID-19 pandemic to March 2021. Individuals with a score of ≥ 10 on the Geriatric Depression Scale 15 (GDS 15) were excluded. The survey items included the 25-question Geriatric Locomotive Function Scale (GLFS25), GDS 15, and other basic attributes. Those with scores of 5 to 9 on the GDS 15 and those with scores of 0 to 4 were assigned to the depressive symptoms (DS) group and the non-DS group, respectively. Statistical analysis was performed using two-way analysis of variance. The Mann-Whitney U test was used for comparisons between the groups. RESULTS: In total, 187 patients were included in the analysis, excluding 7 patients. GLFS 25 showed a significant increase in scores at the second and third time points compared with baseline, and a main effect was confirmed in both groups, with no interaction effect. The second time, the score was 10.0 ± 8.5 and 13.7 ± 10.5 in the non-DS and DS groups, respectively. The third time, the non-DS and DS groups scored 10.8 ± 10.5 and 14.9 ± 10.1 points, respectively, indicating a significant difference. CONCLUSIONS: Our results revealed that the increase in the GLFS 25 score in community-dwelling older adults during the COVID-19 pandemic was related to their DS during normal times before the pandemic. Evaluating such individuals and providing social support may effectively reduce the deterioration of the GLFS 25 score.


Subject(s)
COVID-19 , Depression , Male , Humans , Female , Aged , Aged, 80 and over , Depression/diagnosis , Depression/epidemiology , Depression/psychology , Independent Living , Pandemics , COVID-19/epidemiology , Surveys and Questionnaires
14.
World Journal of Dentistry ; 14(2):161-169, 2023.
Article in English | Scopus | ID: covidwho-2323913

ABSTRACT

Aim: To evaluate the knowledge and attitude of dentists toward geriatric dental care during the coronavirus 2019 (COVID-19) pandemic. Materials and methods: An online questionnaire survey was conducted among a self-selected sample of dentists from different parts of India. The first part of the questionnaire comprised 12 items that collected information regarding knowledge, and the second part comprised 14 items that assessed the attitude of participants toward geriatric dental care during the COVID-19 pandemic. Results: Evaluating knowledge–65% of participants were aware of guidelines by the Ministry of Health and Family Welfare (MOHFW) for dentists that should be practiced during the COVID-19 pandemic, and 93.6% were aware of post-COVID complications present in older adults after recovering from the acute phase of the disease. Evaluating attitude: A total of 69.8% of them found it difficult to deliver dental care to geriatric patients after following all the COVID-19 practice guidelines, and 97.1% of participants were willing to treat a post-COVID older adult in the dental clinic. Conclusion: A total of 69.8% of them found it difficult to deliver dental care to geriatric patients after following all the COVID-19 practice guidelines. Around 31.4% of dentists were not aware of the precautions to be taken to treat older adults with post-COVID complications. Hence there is a need for further studies on post-COVID complications and guidelines for treating the elderly during the pandemic. Clinical significance: As a consequence of newly emerged barriers and post-COVID complications, much poorer oral health outcomes might occur among geriatric patients in the near future. Hence it is important to understand the knowledge and attitude of dentists towards geriatric dental care in order to equip the already small workforce interested in geriatric oral health care. © The Author(s). 2023.

15.
BMJ Open ; 13(5): e067786, 2023 05 19.
Article in English | MEDLINE | ID: covidwho-2326662

ABSTRACT

INTRODUCTION: Older people were at particular risk of morbidity and mortality during COVID-19. Consequently, they experienced formal (externally imposed) and informal (self-imposed) periods of social isolation and quarantine. This is hypothesised to have led to physical deconditioning, new-onset disability and frailty. Disability and frailty are not routinely collated at population level but are associated with increased risk of falls and fractures, which result in hospital admissions. First, we will examine incidence of falls and fractures during COVID-19 (January 2020-March 2022), focusing on differences between incidence over time against expected rates based on historical data, to determine whether there is evidence of new-onset disability and frailty. Second, we will examine whether those with reported SARS-CoV-2 were at higher risk of falls and fractures. METHODS AND ANALYSIS: This study uses the Office for National Statistics (ONS) Public Health Data Asset, a linked population-level dataset combining administrative health records with sociodemographic data of the 2011 Census and National Immunisation Management System COVID-19 vaccination data for England. Administrative hospital records will be extracted based on specific fracture-centric International Classification of Diseases-10 codes in years preceding COVID-19 (2011-2020). Historical episode frequency will be used to predict expected admissions during pandemic years using time series modelling, if COVID-19 had not occurred. Those predicted admission figures will be compared with actual admissions to assess changes in hospital admissions due to public health measures comprising the pandemic response. Hospital admissions in prepandemic years will be stratified by age and geographical characteristics and averaged, then compared with pandemic year admissions to assess more granular changes. Risk modelling will assess risk of experiencing a fall, fracture or frail fall and fracture, if they have reported a positive case of COVID-19. The combination of these techniques will provide insight into changes in hospital admissions from the COVID-19 pandemic. ETHICS AND DISSEMINATION: This study has approval from the National Statistician's Data Ethics Advisory Committee (NSDEC(20)12). Results will be made available to other researchers via academic publication and shared via the ONS website.


Subject(s)
COVID-19 , Fractures, Bone , Frailty , Humans , Aged , COVID-19/epidemiology , Frailty/epidemiology , Pandemics , SARS-CoV-2 , Time Factors , COVID-19 Vaccines , Electronic Health Records , Fractures, Bone/epidemiology , Risk Assessment , Hospitals
16.
BMC Geriatr ; 23(1): 295, 2023 05 15.
Article in English | MEDLINE | ID: covidwho-2327401

ABSTRACT

INTRODUCTION: Geriatric assessment (GA) is widely used to detect vulnerability in older patients. As this process is time-consuming, prescreening tools have been developed to identify patients at risk for frailty. We aimed to assess whether the Geriatric 8 (G8) or the Korean Cancer Study Group Geriatric Score (KG-7) shows better performance in identifying patients who are in need of full GA. MATERIALS AND METHODS: A consecutive series of patients aged ≥ 60 years with colorectal cancer were included. The sensitivity, specificity, predictive value, and 95% confidence intervals (95% CI) were calculated for the G8 and the KG-7 using the results of GA as the reference standard. ROC(Receiver Operating Characteristic) was used to evaluate the accuracy of the G8 and the KG-7. RESULTS: One hundred four patients were enrolled. A total of 40.4% of patients were frail according to GA, and 42.3% and 50.0% of patients were frail based on the G8 and the KG-7, respectively. The sensitivity and specificity of the G8 were 90.5% (95% CI: 77.4-97.3%) and 90.3% (95% CI: 80.1-96.4%), respectively. For the KG-7, the sensitivity and specificity were 83.3% (95% CI: 68.6-93.0%) and 72.6% (95% CI: 59.8-83.1%), respectively. Compared to the KG-7, the G8 had a higher predictive accuracy (AUC: (95% CI): 0.90 (0.83-0.95) vs. 0.78 (0.69-0.85); p < 0.01). By applying the G8 and the KG-7, 60 and 52 patients would not need a GA assessment, respectively. CONCLUSION: Both the G8 and the KG-7 showed a great ability to detect frailty in older patients with colorectal cancer. In this population, compared to the KG-7, the G8 had a better performance in identifying those in need of a full Geriatric Assessment.


Subject(s)
Colorectal Neoplasms , Frailty , Neoplasms , Aged , Humans , Frailty/diagnosis , Frail Elderly , Early Detection of Cancer , Neoplasms/diagnosis , Sensitivity and Specificity , Geriatric Assessment/methods , Colorectal Neoplasms/diagnosis
17.
International Journal of Pharmaceutical and Clinical Research ; 15(4):427-434, 2023.
Article in English | EMBASE | ID: covidwho-2318470

ABSTRACT

Introduction: COVID-19 is a widespread disease having more impact on elderly as compared to younger age group. [2] Although many parameters have emerged as predictors of prognosis of COVID-19, a simple clinical score at baseline can be used for early risk stratification. NEWS2 (National Early Warning Score) is one such scoring system which was originally developed to improve detection of deterioration in acutely ill patients.[8] Therefore, the present study has been conducted to assess the effectiveness of NEWS2 in predicting critical outcomes and mortality in geriatric patients with COVID-19. Material(s) and Method(s): A cross sectional Observational study was done on 200 Geriatric patients hospitalised with confirmed COVID-19 between December 2020 to November 2022. Baseline NEWS2 score was calculated. The sensitivity, specificity, Positive Predictive Value and Negative Predictive Value were established for NEWS2 score of 5 or above. Result(s): In critical group, all 109 (100%) patients' deterioration was predicted, and in non-critical group, in 14 (15.4%) patients non deterioration was predicted while 77 (84.6%) patients' deterioration was predicted. Statistically significant association has been observed between the critical, non-critical groups and NEWS2 scale (P=0.001). Deterioration was predicted by NEWS2 scale in all the critical patients. Conclusion(s): NEWS2 score of 5 or more on admission predicts poor prognosis in geriatric patients with COVID-19 with good sensitivity and it can easily be applied for risk stratification at baseline. We recommend further studies in the Indian setting to validate this simple score and use it further in Geriatric patients with COVID-19.Copyright © 2023, Dr Yashwant Research Labs Pvt Ltd. All rights reserved.

18.
International Journal of Pharmaceutical and Clinical Research ; 15(4):420-426, 2023.
Article in English | EMBASE | ID: covidwho-2318469

ABSTRACT

Introduction: COVID-19 pandemic affected 44,696,984 people in India Geriatric (age 60 years and above) population is increasing globally. Older adults have been affected badly with COVID-19 Neutrophil lymphocyte ratio (NLR) is used in several diseases as an inflammatory marker in predicting prognosis. According to a recent study patients with severe COVID-19 are reported to have higher Neutrophil lymphocyte ratio ( NLR). In this study we aimed to assess the accuracy of Neutrophil lymphocyte ratio (NLR) as a predictor of disease severity and mortality in geriatric patients with COVID-19. Material(s) and Method(s): 200 geriatric inpatients infected with COVID-19 were included in the study. Neutrophil lymphocyte ratio (NLR) at admission was recorded. Neutrophil lymphocyte ratio (NLR) cutoff was taken 3.5. Patients were categorized into mild, moderate, severe and critical cases according to criteria given by Maharashtra Task Force. Relationship between Neutrophil lymphocyte ratio (NLR) and disease outcome was assessed. A p value < 0.05 was taken as statistically significant. Result(s): The mean age of study sample was 69.00 +/-7.09 years. A significant association was found between Neutrophil lymphocyte ratio (NLR) and disease severity (p-0.048) as well as mortality (p-0.041).Copyright © 2023, Dr Yashwant Research Labs Pvt Ltd. All rights reserved.

19.
Dissertation Abstracts International Section A: Humanities and Social Sciences ; 84(8-A):No Pagination Specified, 2023.
Article in English | APA PsycInfo | ID: covidwho-2318248

ABSTRACT

Social and physical frailty are common geriatric syndromes related to adverse health outcomes, including falls, hospitalization, institutionalization, and death. Social frailty leads to physical frailty in older adults who were not frail. Previous studies have demonstrated that pet ownership and robotic pets have physical and mental health benefits for older adults;however, no studies were found investigating the impact of robotic pets on social and physical frailty in community-dwelling older adults. The purpose of this study was to investigate the impact of a robotic pet on social and physical frailty in community-dwelling older adults using the Technology Acceptance Model as a framework. This was a clinical trial of adults aged 65 and over, hospitalized at a community hospital in Westchester County, New York. Intervention group participants received a robotic pet, and control group participants received usual post-discharge care. Participants were assessed at enrollment and at the 30-day discharge point using the Questionnaire to Define Social Frailty Status, FRAIL Questionnaire, the Geriatric Depression Scale Short Form, and the Short Portable Mental Status Questionnaire. For this study ,220 participants were enrolled;107 in the intervention group and 113 in the control group. Continuous outcomes were compared between groups using t-tests or Wilcoxon rank sum tests, as appropriate. Categorical outcomes were compared between groups using chi-square tests or Fisher's exact tests, as appropriate. The threshold for statistical significance was considered a p value of less than 0.05. There was no significant change in social frailty or physical frailty, cognitive status, or depression between the two groups. Participants who enjoyed doing things with their robotic pet had a statistically significant improvement in their SPMSQ scores (p = 0.02), which indicated a positive effect on cognition in participants who used their pet more. Prevalence of social frailty was high, likely attributable to pandemic control measures and unlikely to change on the social frailty questionnaire used in this study due to the ongoing pandemic. In contrast to this study, previous research has shown that robotic pets were effective for improving well-being in older adults and showed more positive impact in a group setting compared to individual use. A significant limitation of this study was that it took place during the COVID-19 pandemic. Other limitations were related to self-report of some measures which may introduce bias. Additionally, the social frailty questionnaire has not been validated in diverse populations;thus, its validity in the study population is not known. The geographic area where the study took place is non-diverse, which may impact generalizability to wider populations. The robotic pet positively impacted cognitive status in participants who reported they enjoyed doing activities with their pet. This supports the theoretical premise of this study that greater use of the robotic pet would yield greater benefit. Regarding implications, technology is an important tool to ameliorate social and physical frailty, especially in light of pandemic-related restrictions where in-person socialization is restricted. More research is needed on the impact of robotic pets in older adults living at home, particularly on social frailty, loneliness, and cognitive status, with larger sample sizes and diverse populations. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

20.
Nordic Journal of Music Therapy ; : No Pagination Specified, 2023.
Article in English | APA PsycInfo | ID: covidwho-2314907

ABSTRACT

Introduction Delirium is an acute alteration in attention, awareness, arousal, and cognition, precipitated by a sudden illness and highly prevalent in older, frail and acutely hospitalized patients. It is associated with poor outcomes, and few effective treatment alternatives. Non-pharmacological interventions and music show promising effects, warranting further research. This pilot randomized repeated measures trial aims to test feasibility of the trial methodology, acceptability, fidelity and safety of the music interventions, suitability of the effect-outcomes. and preliminary effectiveness. Method Acute geriatric patients with delirium or subsyndromal delirium will be randomized to Preferred Recorded Music (n = 30) or Preferred Live Music (n = 30), delivered for 30 minutes, over three consecutive days. Planned feasibility outcomes will comprise recruitment rate, retention and attrition rates, percentage of adherence, deviations rates, and success of treatment fidelity. Clinical outcomes will include: (a) trajectory of delirium symptoms: level of arousal as assessed by Observational Scale of Level of Arousal (OSLA) and modified Richmond Agitation Sedation Scale (mRASS);attention, assessed using backwards tests and digit span tests;orientation and short-term memory, assessed using recall tasks and orientation questions from Memorial Delirium Assessment Scale, (b) duration of delirium, (c) length of hospital stay, and (d) use of PRN medication (benzodiazepines and antipsychotics). Discussion The trial will provide results needed to design a subsequent sufficiently powered RCT, informing on the expected recruitment, feasibility and acceptability of the interventions and assessments and preliminary effectiveness (PsycInfo Database Record (c) 2023 APA, all rights reserved)

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